Common Drugs Used for Leiomyosarcoma

 In addition to these therapies below, please always search for clinical trials BEFORE you decide on your treatment. Many trials combine standard chemos with newer promising drugs. If you have already had the chemo, you will likely not be eligible for the new trial combining that chemo with the newer drug. Search trials for leiomyosarcoma (or sarcoma / solid tumors) on https://clinicaltrials.gov/

Traditional Cytotoxic Chemos (kills all fast growing cells)

Adriamycin (doxorubicin)

Adriamycin with Ifex (doxorubicin with ifosfamide)

Doxil ((doxorubicin hydrochloride liposome)

DTIC (dacarbazine)

Gemzar and Taxotere (gemcitabine and docetaxel)

Yondelis (trabectedin)

Temodar (temozolomide)

Targeted Therapy (targets proteins that control how cancer cells grow, spread and divide)

Votrient (pazopanib hydrochloride)

PARP inhibitors

• Lynparza (olaparib)

• Rubraca (rucaparib)

• Zejula (niraparib)

Immunotherapy (helps your immune system recognize and destroy cancer cells)

Opdivo (nivolumab)

Yervoy (ipilimumab)

Hormone Therapy (slows or stops the growth of cancer that uses hormones to grow)

Aromatase inhibitors

• Arimidex (anastrozole)

• Aromasin (exemestane)

• Femara (letrozole)