This fund was created to help raise money to find a cure for Leiomyosarcoma (LMS), a rare, aggressive form of cancer. All funds raised are donated to Dr. Matt van de Rijn of Stanford University and his targeted therapy research. Dr. Matt van de Rijn is focusing on three proteins common in LMS and believes in targeted therapy as an alternative treatment. This form of treatment targets proteins that aren’t found in normal, healthy cells and would cause less damage to the patient’s body, increasing the amount of drugs a patient’s body can withstand as opposed to chemotherapy. The three proteins include ROR2, CD47 and CSF1. Studies will focus on antibodies that would prevent ROR2 from forming. By preventing CD47 from forming, macrophages (immune cells) are able to eliminate LMS. CSF1 is embedded inside the tumor and gathers macrophages and uses the cells to create new blood vessels to support the tumor. Investigators will look at various ways of disrupting the process.
If you would like to make a donation in honor of Weinstock family go to the the boxes to the right.
About Leiomyosarcoma Support & Direct Research Foundation (LMSDR)
Leiomyosarcoma Support & Direct Research is an all volunteer organization which the Weinstock family supported. We are proud to have Patient Registry to collect data, and ran successful blood collections for study. We have brought patients and loved ones together from all over the minimal amount of expenses as possible, to ensure your money goes directly to funding promising research for leiomyosarcoma specifically. You can volunteer, put on fundraisers, promote LMS awareness and ask your employer for matched funds. Please consider making a donation and helping us Work, not wish, for treatments that will work for us. We have been a 501(C) (3) since 2006 and a tax-free charity.