This memorial fund is being set up in honor of Regina Lea Pflanz Hottois. She was the wife to Ryan (50), mother to Sophia Grace (18) and Gavin Michael (16), sister to Allison and Richard, daughter of Rick and Jeannie, aunt to Ryan (25), Payton (20), Richard (18), Abigail (17), Charleston (4), and Grey (6months). She practiced nursing for 25 years, and was known as a kind, loving, crafty, compassionate Harry Potter fan and friend to all. She battled LMS for almost a year, before passing away on January 22, 2021. On March 4, 2020, Regina was diagnosed with leiomyosarcoma after being rushed to the ER due to severe hemorrhaging the night before. She then received an emergency hysterectomy that night, stayed in the hospital for 10 more days, recovered from surgery for 6 weeks all while battling an ileus, to later begin her first chemo treatment on April 24 through University of Louisville hospital. She did these treatments throughout the summer, but towards the end of July, she received a CT scan that showed none of the chemo had worked, and the cancer had spread more throughout her body. Since LMS is so extremely rare, the Louisville doctors knew she needed more specialized care. That being said, on August 10, she flew to MDAnderson Cancer Center for more aggressive treatment that specifically targeted leiomyosarcoma. This treatment ended up being way too aggressive, causing the doctors to terminate her treatment and send her home. On October 1, 2020 (her son’s 16th birthday) she flew into Norton’s Hospital in downtown Louisville. On October 4, she was released into the care of her loving family. Towards the end of the month, Regina started her third different chemo treatment with her third different oncology team. Despite all of the chemo, blood transfusions, surgery, and pain she endured, test results in early January showed that none of her chemo was working, and was just giving her cancer more time to grow and spread. She knew the end of her life was near at this point, but continued to be kind and loving as she accepted her fate. About 2 weeks later, on January 17, 2021, she was hospitalized for the final time due to a small bowel obstruction, passing away 5 days later. Our hearts are forever heavy as we mourn the loss of our beloved Regina. One thing Regina would say is that she wished LMS had more research funds, especially because it is so rare. As her words still ring loud and clear in our minds, we would deeply appreciate donations to this fund in her name in order to raise awareness for LMS and honor her blessed memory and soul.