This fund was created to help raise money to find a cure for Leiomyosarcoma (LMS), a rare, aggressive form of cancer. All funds raised are donated to Dr. Matt van de Rijn of Stanford University and his targeted therapy research. Dr. Matt van de Rijn is focusing on three proteins common in LMS and believes in targeted therapy as an alternative treatment. This form of treatment targets proteins that aren’t found in normal, healthy cells and would cause less damage to the patient’s body, increasing the amount of drugs a patient’s body can withstand as opposed to chemotherapy. The three proteins include ROR2, CD47 and CSF1. Studies will focus on antibodies that would prevent ROR2 from forming. By preventing CD47 from forming, macrophages (immune cells) are able to eliminate LMS. CSF1 is embedded inside the tumor and gathers macrophages and uses the cells to create new blood vessels to support the tumor. Investigators will look at various ways of disrupting the process.
If you would like to make a donation to LMSdr, please click here . Please mention the name ’Weinstock’ on your check or on-line donation. (When donating through PayPal, you can use the Designation Box to specify a Fund.)